PSIO 6310 Functional Genomics and Proteomics

3 SCH. The purpose of this course is to introduce students to concepts and methods used in defining a database of tissue specific and disease specific protein expression. Topics to be discussed include: 1) genome mining; 2) transcriptome mining and validation; 3) proteome mining by 2-dimensional gel electrophoresis, mass spectrometry and protein chips; 4) protein structure determination; 5) protein structure prediction based on gene sequence; 6) protein function prediction and analysis; 7) protein-protein interactions; and 8) protein localization. Cross-listed with CBAN 6341.