Mar 28, 2024  
2018-2019 Catalog 
    
2018-2019 Catalog [ARCHIVED CATALOG]

PHRM 6360 Nuc Rec Superfamily


3 SCH. Members of the Nuclear Receptor Superfamily play a role in a vast array of physiologic processes. Originally discovered as steroid hormone receptors, they are now known to be receptors for such diverse ligands as thyroid hormone and vitamin D. A large number of receptors regulate transcription in the absence of binding hormone, as well, serving as targets of other signaling mechanisms. The course provides an overview of this extensive field. It will include lectures and discussion of structure/functional analysis, mechanisms of action, and examples of diseases associated with nuclear receptor dysfunction.
Offered Every other Spring - Odd Years
Letter Grade