MOMG 6303 Statistical Genetics

3 SCH. In this course, the students will explore the basic premises of underlying statistical models for genetic data and be able to understand how genetic variation can be interpreted in terms of probability models. Students will learn the principles of conducting quantitative analyses of date for determining 1) when to infer positive family history is regarded as a risk factor for disease; 2) how to proceed with establishing genetics as a significant risk factor; 3) mode of inheritance; and 4) localization of genes underlining a familial trait. The concept of interactions of genetic and environmental /life style risk factors and the methods to detect such effects will also be addressed. Stress will be placed on concepts and assumptions and their implications for finding genes for diseases, localization of disease-susceptibility genes, and estimation of genetic risks. Also emphasized in this course will be the application of statistics in societal problems where genetic principles may be useful. Prerequisites: calculus and statistics. Offered in the spring semester, odd years. Letter Grade